G protein signaling in the parasite Entamoeba histolytica

Dustin_and_Adam

Stellar MD/PhD student Dustin Bosch, pictured above in a tie(!), wrote a thorough (and thoroughly-impressive) review of current understanding of heterotrimeric G protein and small GTPase signaling in the parasite Entamoeba histolytica — the causative agent of amoebic dysentery. Fellow lab star Dr. Adam Kimple, MD/PhD, is also depicted above and has also contributed to the Siderovski lab’s foray into this infectious disease research thread.

 

Trophozoites of Entamoeba histolytica with ing...

Trophozoites of Entamoeba histolytica with ingested erythrocytes (trichrome stain). The ingested erythrocytes appear as dark inclusions. Erythrophagocytosis is the only characteristic that can be used to differentiate morphologically E. histolytica from the nonpathogenic E. dispar. In these specimens, the parasite nuclei have the typical small, centrally located karyosome, and thin, uniform peripheral chromatin. (Photo credit: Wikipedia)

Experimental & Molecular Medicine – G protein signaling in the parasite Entamoeba histolytica.
Exp Mol Med. 2013 Mar 22;45:e15. doi: 10.1038/emm.2013.30.

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s